C-C Bond Formation
Classic Method
Radical carbon-bond forming reactions (i.e. Wurtz reaction, acyloin condensation, etc.) are fundamental to organic synthesis. The majority of carbon-centered radicals undergo dimerization but these reactions are usually not atom economical or chemically selective increasing the costs for synthesis.
SiGNa’s Method
Carbon bond formations with SiGNa materials are able to be performed in both atom and process efficient syntheses in turn reducing cost to the end-user. The reaction conditions afford much cleaner products, safer reactive species, and milder conditions.
Benefits
- Provides a smooth solution process at room temperature
- Can be performed in either batch or continuous-flow reactor setup
- Enhanced selectivity and kinetics of reaction
- By-products and salts removed through binding to SiGNa material
Recommended Products for C-C Bond Formation
Alkali Metal-Silica Gel
Highly loaded, free-flowing stabilized alkali metal powders with reactivity as high as the parent metal.
Alkali Metal-Alumina Gel
Highly loaded, atomically dispersed alkali metal powder (includes lithium) wtih more extensive reactivity than the parent metal.
Organolithium-Alumina Gel
Bottle-able solid powdery reagent loaded up to 10 mmol/g; storable under nitrogen with infinite shelf life; extended range of organolithium nucleophiles
SiGNa Spotlight
New Discoveries
Currently SiGNa is working on the next element in the alkali metal family, Lithium. A number of new discoveries have been made. Read More